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Zytiga 250 mg acetate works by inhibiting certain "enzymes" in the adrenal glands that are responsible for the production of androgens. For this reason, there is an increased risk of excessive production of mineral corticosteroids in the body when taking Zytiga 250 mg acetate. As a result, Zytiga 250 mg acetate can cause hypertension [high blood pressure], hypokalemia [low potassium levels in the blood], and fluid retention. Because of this risk, Zytiga 250 mg acetate should be used with caution in patients with a strong cardiovascular history, and patients should be closely monitored for these symptoms. Dosing in conjunction with prednisone will reduce the risk of mineralocorticoid excess. Before starting treatment with Zytiga 250 mg acetate, be sure to tell your doctor about any other medicines you are taking (including prescription, over-the-counter, vitamins, herbal remedies, etc.). Do not take aspirin, products containing aspirin, unless authorized by your doctor. Zytiga 250 mg acetate is not currently indicated for use in women. However, if women are prescribed Zytiga 250 mg (Abiraterone) acetate, getting pregnant should be avoided and the woman should not breastfeed. Zytiga 250 mg acetate is not currently indicated for use in women. Zytiga 250 mg acetate should not be given to women who are pregnant or intending to become pregnant. Pregnancy Category X (Zytiga 250 mg acetate may cause harm to the fetus when administered to a pregnant woman. If a woman becomes pregnant while taking Zytiga 250 mg acetate, treatment should be stopped immediately and the woman should be consulted).
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